LPCAT1-MED13 Fusion FISH Probe
The LPCAT1-MED13 Fusion FISH Probe is used to confirm a fusion of the LPCAT1 and MED13 genes. The fusion of the LPCAT1 and MED13 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPCAT1-MED13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-RERE | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-REOR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-REGO | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-REGR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-REAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-ORRE | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-OROR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-ORGO | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GORE | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GOOR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GOGO | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GOGR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GRRE | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GROR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GRGO | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GRGR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-AQRE | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-AQOR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-AQGO | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-AQGR | 20 (40 μL) | 200 μL |
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| LPCAT1-MED13-20-AQAQ | 20 (40 μL) | 200 μL |
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MED13 Gene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 13
Chromosome: CHR17: 60019965 -60142643
Locus: 17q23.2
LPCAT1 Gene Summary
This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016]
Gene Name: Lysophosphatidylcholine Acyltransferase 1
Chromosome: CHR5: 1461541 -1524076
Locus: 5p15.33
Gene Diseases
The LPCAT1 MED13 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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