LONRF1-PSMB7 Fusion FISH Probe
The LONRF1-PSMB7 Fusion FISH Probe is used to confirm a fusion of the LONRF1 and PSMB7 genes. The fusion of the LONRF1 and PSMB7 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LONRF1-PSMB7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-RERE | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-REOR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-REGO | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-REGR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-REAQ | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-ORRE | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-OROR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-ORGO | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-ORAQ | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GORE | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GOOR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GOGO | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GOGR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GOAQ | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GRRE | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GROR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GRGO | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GRGR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-GRAQ | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-AQRE | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-AQOR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-AQGO | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-AQGR | 20 (40 μL) | 200 μL |
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| LONRF1-PSMB7-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMB7 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]
Gene Name: Proteasome Subunit Beta 7
Chromosome: CHR9: 127115743 -127177721
Locus: 9q33.3
LONRF1 Gene Summary
The LON Peptidase N-terminal Domain And Ring Finger 1 (LONRF1) gene is located on chr8 :12579405-12612992 at 8p23.1.
Gene Name: LON Peptidase N-terminal Domain And Ring Finger 1
Chromosome: CHR8: 12579405 -12612992
Locus: 8p23.1
Gene Diseases
The LONRF1 PSMB7 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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