LNPEP-GPBP1 Fusion FISH Probe
The LNPEP-GPBP1 Fusion FISH Probe is used to confirm a fusion of the LNPEP and GPBP1 genes. The fusion of the LNPEP and GPBP1 genes has been associated with Kidney Chromophobe. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LNPEP-GPBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-RERE | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-REOR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-REGO | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-REGR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-OROR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GORE | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GROR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| LNPEP-GPBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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LNPEP Gene Summary
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Leucyl And Cystinyl Aminopeptidase
Chromosome: CHR5: 96271345 -96365115
Locus: 5q15
GPBP1 Gene Summary
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Gene Name: GC-rich Promoter Binding Protein 1
Chromosome: CHR5: 56469774 -56560506
Locus: 5q11.2
Gene Diseases
The LNPEP GPBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Chromophobe |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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