LNPEP-FLT4 Fusion FISH Probe
The LNPEP-FLT4 Fusion FISH Probe is used to confirm a fusion of the LNPEP and FLT4 genes. The fusion of the LNPEP and FLT4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LNPEP-FLT4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-RERE | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-REOR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-REGO | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-REGR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-REAQ | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-ORRE | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-OROR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-ORGO | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-ORAQ | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GORE | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GOOR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GOGO | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GOGR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GOAQ | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GRRE | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GROR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GRGO | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GRGR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-GRAQ | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-AQRE | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-AQOR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-AQGO | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-AQGR | 20 (40 μL) | 200 μL |
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| LNPEP-FLT4-20-AQAQ | 20 (40 μL) | 200 μL |
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FLT4 Gene Summary
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
Gene Name: Fms Related Tyrosine Kinase 4
Chromosome: CHR5: 180028505 -180076624
Locus: 5q35.3
LNPEP Gene Summary
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Leucyl And Cystinyl Aminopeptidase
Chromosome: CHR5: 96271345 -96365115
Locus: 5q15
Gene Diseases
The LNPEP FLT4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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