LMBRD1-COL9A1 Fusion FISH Probe
The LMBRD1-COL9A1 Fusion FISH Probe is used to confirm a fusion of the LMBRD1 and COL9A1 genes. The fusion of the LMBRD1 and COL9A1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LMBRD1-COL9A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-RERE | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-REOR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-REGO | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-REGR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-REAQ | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-ORRE | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-OROR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-ORGO | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GORE | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GOOR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GOGO | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GOGR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GRRE | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GROR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GRGO | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GRGR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-AQRE | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-AQOR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-AQGO | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-AQGR | 20 (40 μL) | 200 μL |
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| LMBRD1-COL9A1-20-AQAQ | 20 (40 μL) | 200 μL |
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COL9A1 Gene Summary
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type IX Alpha 1 Chain
Chromosome: CHR6: 70925742 -71012786
Locus: 6q13
LMBRD1 Gene Summary
This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.[provided by RefSeq, Oct 2009]
Gene Name: LMBR1 Domain Containing 1
Chromosome: CHR6: 70385640 -70507049
Locus: 6q13
Gene Diseases
The LMBRD1 COL9A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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