LMAN2L-FAM178B Fusion FISH Probe
The LMAN2L-FAM178B Fusion FISH Probe is used to confirm a fusion of the LMAN2L and FAM178B genes. The fusion of the LMAN2L and FAM178B genes has been associated with Head And Neck Squamous Cell Carcinoma , and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LMAN2L-FAM178B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-RERE | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-REOR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-REGO | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-REGR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-REAQ | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-ORRE | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-OROR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-ORGO | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-ORAQ | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GORE | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GOOR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GOGO | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GOGR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GOAQ | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GRRE | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GROR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GRGO | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GRGR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-GRAQ | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-AQRE | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-AQOR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-AQGO | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-AQGR | 20 (40 μL) | 200 μL |
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| LMAN2L-FAM178B-20-AQAQ | 20 (40 μL) | 200 μL |
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FAM178B Gene Summary
The Family With Sequence Similarity 178 Member B (FAM178B) gene is located on chr2 :97541618-97652301 at 2q11.2.
Gene Name: Family With Sequence Similarity 178 Member B
Chromosome: CHR2: 97541618 -97652301
Locus: 2q11.2
LMAN2L Gene Summary
This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway. [provided by RefSeq, Apr 2016]
Gene Name: Lectin, Mannose Binding 2 Like
Chromosome: CHR2: 97371666 -97405813
Locus: 2q11.2
Gene Diseases
The LMAN2L FAM178B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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