LLGL1-TLN2 Fusion FISH Probe
The LLGL1-TLN2 Fusion FISH Probe is used to confirm a fusion of the LLGL1 and TLN2 genes. The fusion of the LLGL1 and TLN2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LLGL1-TLN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-RERE | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-REOR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-REGO | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-REGR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-REAQ | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-ORRE | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-OROR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-ORGO | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GORE | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GOOR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GOGO | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GOGR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GRRE | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GROR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GRGO | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GRGR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-AQRE | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-AQOR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-AQGO | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-AQGR | 20 (40 μL) | 200 μL |
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| LLGL1-TLN2-20-AQAQ | 20 (40 μL) | 200 μL |
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LLGL1 Gene Summary
This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Gene Name: LLGL1, Scribble Cell Polarity Complex Component
Chromosome: CHR17: 18128935 -18148188
Locus: 17p11.2
TLN2 Gene Summary
This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Gene Name: Talin 2
Chromosome: CHR15: 62939509 -63136829
Locus: 15q22.2
Gene Diseases
The LLGL1 TLN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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