LIMA1-ANO6 Fusion FISH Probe
The LIMA1-ANO6 Fusion FISH Probe is used to confirm a fusion of the LIMA1 and ANO6 genes. The fusion of the LIMA1 and ANO6 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LIMA1-ANO6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-RERE | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-REOR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-REGO | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-REGR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-REAQ | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-ORRE | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-OROR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-ORGO | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-ORAQ | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GORE | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GOOR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GOGO | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GOGR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GOAQ | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GRRE | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GROR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GRGO | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GRGR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-GRAQ | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-AQRE | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-AQOR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-AQGO | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-AQGR | 20 (40 μL) | 200 μL |
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| LIMA1-ANO6-20-AQAQ | 20 (40 μL) | 200 μL |
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LIMA1 Gene Summary
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]
Gene Name: LIM Domain And Actin Binding 1
Chromosome: CHR12: 50569562 -50677353
Locus: 12q13.12
ANO6 Gene Summary
This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Gene Name: Anoctamin 6
Chromosome: CHR12: 45609769 -45834187
Locus: 12q12
Gene Diseases
The LIMA1 ANO6 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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