LHFPL2-PTPRK Fusion FISH Probe
The LHFPL2-PTPRK Fusion FISH Probe is used to confirm a fusion of the LHFPL2 and PTPRK genes. The fusion of the LHFPL2 and PTPRK genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LHFPL2-PTPRK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-RERE | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-REOR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-REGO | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-REGR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-OROR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GORE | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GROR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| LHFPL2-PTPRK-20-AQAQ | 20 (40 μL) | 200 μL |
|
PTPRK Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type K
Chromosome: CHR6: 128289923 -128841870
Locus: 6q22.33
LHFPL2 Gene Summary
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: LHFPL Tetraspan Subfamily Member 2
Chromosome: CHR5: 77781037 -77944648
Locus: 5q14.1
Gene Diseases
The LHFPL2 PTPRK Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|