LGR6-NAV1 Fusion FISH Probe
The LGR6-NAV1 Fusion FISH Probe is used to confirm a fusion of the LGR6 and NAV1 genes. The fusion of the LGR6 and NAV1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LGR6-NAV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-RERE | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-REOR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-REGO | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-REGR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-REAQ | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-ORRE | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-OROR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-ORGO | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GORE | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GOOR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GOGO | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GOGR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GRRE | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GROR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GRGO | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GRGR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-AQRE | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-AQOR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-AQGO | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-AQGR | 20 (40 μL) | 200 μL |
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| LGR6-NAV1-20-AQAQ | 20 (40 μL) | 200 μL |
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LGR6 Gene Summary
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: Leucine Rich Repeat Containing G Protein-coupled Receptor 6
Chromosome: CHR1: 202163117 -202288889
Locus: 1q32.1
NAV1 Gene Summary
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Gene Name: Neuron Navigator 1
Chromosome: CHR1: 201617449 -201796102
Locus: 1q32.1
Gene Diseases
The LGR6 NAV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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