LGR5-FAM19A2 Fusion FISH Probe
The LGR5-FAM19A2 Fusion FISH Probe is used to confirm a fusion of the LGR5 and FAM19A2 genes. The fusion of the LGR5 and FAM19A2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LGR5-FAM19A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-RERE | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-REOR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-REGO | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-REGR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-REAQ | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-ORRE | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-OROR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-ORGO | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GORE | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GOOR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GOGO | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GOGR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GRRE | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GROR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GRGO | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GRGR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-AQRE | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-AQOR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-AQGO | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-AQGR | 20 (40 μL) | 200 μL |
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| LGR5-FAM19A2-20-AQAQ | 20 (40 μL) | 200 μL |
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LGR5 Gene Summary
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Name: Leucine Rich Repeat Containing G Protein-coupled Receptor 5
Chromosome: CHR12: 71833812 -71978621
Locus: 12q21.1
FAM19A2 Gene Summary
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]
Gene Name: Family With Sequence Similarity 19 Member A2, C-C Motif Chemokine Like
Chromosome: CHR12: 62102040 -62586551
Locus: 12q14.1
Gene Diseases
The LGR5 FAM19A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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