LGALS3BP-ELK3 Fusion FISH Probe
The LGALS3BP-ELK3 Fusion FISH Probe is used to confirm a fusion of the LGALS3BP and ELK3 genes. The fusion of the LGALS3BP and ELK3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LGALS3BP-ELK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-RERE | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-REOR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-REGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-REGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-REAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-ORRE | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-OROR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-ORGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GORE | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GOOR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GOGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GOGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GRRE | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GROR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GRGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GRGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-AQRE | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-AQOR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-AQGO | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-AQGR | 20 (40 μL) | 200 μL |
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| LGALS3BP-ELK3-20-AQAQ | 20 (40 μL) | 200 μL |
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ELK3 Gene Summary
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: ELK3, ETS Transcription Factor
Chromosome: CHR12: 96588206 -96661606
Locus: 12q23.1
LGALS3BP Gene Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
Gene Name: Galectin 3 Binding Protein
Chromosome: CHR17: 76967334 -76976061
Locus: 17q25.3
Gene Diseases
The LGALS3BP ELK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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