LDHB-PEX1 Fusion FISH Probe
The LDHB-PEX1 Fusion FISH Probe is used to confirm a fusion of the LDHB and PEX1 genes. The fusion of the LDHB and PEX1 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LDHB-PEX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-RERE | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-REOR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-REGO | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-REGR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-REAQ | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-ORRE | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-OROR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-ORGO | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GORE | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GOOR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GOGO | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GOGR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GRRE | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GROR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GRGO | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GRGR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-AQRE | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-AQOR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-AQGO | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-AQGR | 20 (40 μL) | 200 μL |
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| LDHB-PEX1-20-AQAQ | 20 (40 μL) | 200 μL |
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LDHB Gene Summary
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
Gene Name: Lactate Dehydrogenase B
Chromosome: CHR12: 21788274 -21810789
Locus: 12p12.1
PEX1 Gene Summary
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Peroxisomal Biogenesis Factor 1
Chromosome: CHR7: 92116336 -92157845
Locus: 7q21.2
Gene Diseases
The LDHB PEX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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