LCOR-RBM20 Fusion FISH Probe
The LCOR-RBM20 Fusion FISH Probe is used to confirm a fusion of the LCOR and RBM20 genes. The fusion of the LCOR and RBM20 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LCOR-RBM20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-RERE | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-REOR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-REGO | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-REGR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-REAQ | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-ORRE | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-OROR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-ORGO | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-ORAQ | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GORE | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GOOR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GOGO | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GOGR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GOAQ | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GRRE | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GROR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GRGO | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GRGR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-GRAQ | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-AQRE | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-AQOR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-AQGO | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-AQGR | 20 (40 μL) | 200 μL |
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| LCOR-RBM20-20-AQAQ | 20 (40 μL) | 200 μL |
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LCOR Gene Summary
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008]
Gene Name: Ligand Dependent Nuclear Receptor Corepressor
Chromosome: CHR10: 98592016 -98724198
Locus: 10q24.1
RBM20 Gene Summary
This gene encodes a protein that binds RNA and regulates splicing. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Apr 2014]
Gene Name: RNA Binding Motif Protein 20
Chromosome: CHR10: 112404154 -112599227
Locus: 10q25.2
Gene Diseases
The LCOR RBM20 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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