LAMA5-CABLES2 Fusion FISH Probe
The LAMA5-CABLES2 Fusion FISH Probe is used to confirm a fusion of the LAMA5 and CABLES2 genes. The fusion of the LAMA5 and CABLES2 genes has been associated with Lung Adenocarcinoma, and Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LAMA5-CABLES2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-RERE | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-REOR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-REGO | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-REGR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-REAQ | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-ORRE | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-OROR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-ORGO | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GORE | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GOOR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GOGO | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GOGR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GRRE | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GROR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GRGO | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GRGR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-AQRE | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-AQOR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-AQGO | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-AQGR | 20 (40 μL) | 200 μL |
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| LAMA5-CABLES2-20-AQAQ | 20 (40 μL) | 200 μL |
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LAMA5 Gene Summary
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
Gene Name: Laminin Subunit Alpha 5
Chromosome: CHR20: 60884120 -60942368
Locus: 20q13.33
CABLES2 Gene Summary
The Cdk5 And Abl Enzyme Substrate 2 (CABLES2) gene is located on chr20 :60963685-60982339 at 20q13.33.
Gene Name: Cdk5 And Abl Enzyme Substrate 2
Chromosome: CHR20: 60963685 -60982339
Locus: 20q13.33
Gene Diseases
The LAMA5 CABLES2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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