LAMA3-COX8C Fusion FISH Probe
The LAMA3-COX8C Fusion FISH Probe is used to confirm a fusion of the LAMA3 and COX8C genes. The fusion of the LAMA3 and COX8C genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LAMA3-COX8C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-RERE | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-REOR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-REGO | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-REGR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-REAQ | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-ORRE | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-OROR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-ORGO | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-ORAQ | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GORE | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GOOR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GOGO | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GOGR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GOAQ | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GRRE | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GROR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GRGO | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GRGR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-GRAQ | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-AQRE | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-AQOR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-AQGO | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-AQGR | 20 (40 μL) | 200 μL |
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| LAMA3-COX8C-20-AQAQ | 20 (40 μL) | 200 μL |
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LAMA3 Gene Summary
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Laminin Subunit Alpha 3
Chromosome: CHR18: 21269561 -21535029
Locus: 18q11.2
COX8C Gene Summary
The Cytochrome C Oxidase Subunit 8C (COX8C) gene is located on chr14 :93813536-93814700 at 14q32.12.
Gene Name: Cytochrome C Oxidase Subunit 8C
Chromosome: CHR14: 93813536 -93814700
Locus: 14q32.12
Gene Diseases
The LAMA3 COX8C Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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