LAMA2-NUP107 Fusion FISH Probe
The LAMA2-NUP107 Fusion FISH Probe is used to confirm a fusion of the LAMA2 and NUP107 genes. The fusion of the LAMA2 and NUP107 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LAMA2-NUP107-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-RERE | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-REOR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-REGO | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-REGR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-REAQ | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-ORRE | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-OROR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-ORGO | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-ORAQ | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GORE | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GOOR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GOGO | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GOGR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GOAQ | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GRRE | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GROR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GRGO | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GRGR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-GRAQ | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-AQRE | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-AQOR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-AQGO | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-AQGR | 20 (40 μL) | 200 μL |
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| LAMA2-NUP107-20-AQAQ | 20 (40 μL) | 200 μL |
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LAMA2 Gene Summary
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Laminin Subunit Alpha 2
Chromosome: CHR6: 129204285 -129837710
Locus: 6q22.33
NUP107 Gene Summary
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Name: Nucleoporin 107
Chromosome: CHR12: 69080730 -69136473
Locus: 12q15
Gene Diseases
The LAMA2 NUP107 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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