LACTB2-CYP7B1 Fusion FISH Probe
The LACTB2-CYP7B1 Fusion FISH Probe is used to confirm a fusion of the LACTB2 and CYP7B1 genes. The fusion of the LACTB2 and CYP7B1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LACTB2-CYP7B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-RERE | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-REOR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-REGO | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-REGR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-REAQ | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-ORRE | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-OROR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-ORGO | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GORE | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GOOR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GOGO | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GOGR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GRRE | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GROR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GRGO | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GRGR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-AQRE | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-AQOR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-AQGO | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-AQGR | 20 (40 μL) | 200 μL |
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| LACTB2-CYP7B1-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP7B1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
Gene Name: Cytochrome P450 Family 7 Subfamily B Member 1
Chromosome: CHR8: 65508528 -65711348
Locus: 8q12.3
LACTB2 Gene Summary
The Lactamase Beta 2 (LACTB2) gene is located on chr8 :71549500-71581447 at 8q13.3.
Gene Name: Lactamase Beta 2
Chromosome: CHR8: 71549500 -71581447
Locus: 8q13.3
Gene Diseases
The LACTB2 CYP7B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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