L3MBTL3-WDR37 Fusion FISH Probe
The L3MBTL3-WDR37 Fusion FISH Probe is used to confirm a fusion of the L3MBTL3 and WDR37 genes. The fusion of the L3MBTL3 and WDR37 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| L3MBTL3-WDR37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-RERE | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-REOR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-REGO | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-REGR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-REAQ | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-ORRE | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-OROR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-ORGO | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-ORAQ | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GORE | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GOOR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GOGO | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GOGR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GOAQ | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GRRE | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GROR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GRGO | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GRGR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-GRAQ | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-AQRE | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-AQOR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-AQGO | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-AQGR | 20 (40 μL) | 200 μL |
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| L3MBTL3-WDR37-20-AQAQ | 20 (40 μL) | 200 μL |
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WDR37 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 37
Chromosome: CHR10: 1102775 -1178237
Locus: 10p15.3
L3MBTL3 Gene Summary
This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016]
Gene Name: L3MBTL3, Histone Methyl-lysine Binding Protein
Chromosome: CHR6: 130339727 -130462594
Locus: 6q23.1
Gene Diseases
The L3MBTL3 WDR37 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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