L3MBTL2-EFCAB6 Fusion FISH Probe
The L3MBTL2-EFCAB6 Fusion FISH Probe is used to confirm a fusion of the L3MBTL2 and EFCAB6 genes. The fusion of the L3MBTL2 and EFCAB6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| L3MBTL2-EFCAB6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-RERE | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-REOR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-REGO | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-REGR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-REAQ | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-ORRE | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-OROR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-ORGO | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-ORAQ | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GORE | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GOOR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GOGO | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GOGR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GOAQ | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GRRE | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GROR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GRGO | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GRGR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-GRAQ | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-AQRE | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-AQOR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-AQGO | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-AQGR | 20 (40 μL) | 200 μL |
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| L3MBTL2-EFCAB6-20-AQAQ | 20 (40 μL) | 200 μL |
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EFCAB6 Gene Summary
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: EF-hand Calcium Binding Domain 6
Chromosome: CHR22: 43924623 -44208217
Locus: 22q13.2-q13.31
L3MBTL2 Gene Summary
The L3MBTL2, Polycomb Repressive Complex 1 Subunit (L3MBTL2) gene is located on chr22 :41601312-41627275 at 22q13.2.
Gene Name: L3MBTL2, Polycomb Repressive Complex 1 Subunit
Chromosome: CHR22: 41601312 -41627275
Locus: 22q13.2
Gene Diseases
The L3MBTL2 EFCAB6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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