KSR2-CEP290 Fusion FISH Probe
The KSR2-CEP290 Fusion FISH Probe is used to confirm a fusion of the KSR2 and CEP290 genes. The fusion of the KSR2 and CEP290 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KSR2-CEP290-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-RERE | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-REOR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-REGO | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-REGR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-REAQ | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-ORRE | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-OROR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-ORGO | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-ORAQ | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GORE | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GOOR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GOGO | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GOGR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GOAQ | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GRRE | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GROR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GRGO | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GRGR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-GRAQ | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-AQRE | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-AQOR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-AQGO | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-AQGR | 20 (40 μL) | 200 μL |
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| KSR2-CEP290-20-AQAQ | 20 (40 μL) | 200 μL |
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CEP290 Gene Summary
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]
Gene Name: Centrosomal Protein 290
Chromosome: CHR12: 88442789 -88535993
Locus: 12q21.32
KSR2 Gene Summary
The Kinase Suppressor Of Ras 2 (KSR2) gene is located on chr12 :117890816-118406028 at 12q24.22-q24.23.
Gene Name: Kinase Suppressor Of Ras 2
Chromosome: CHR12: 117890816 -118406028
Locus: 12q24.22-q24.23
Gene Diseases
The KSR2 CEP290 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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