KRT19-PFKP Fusion FISH Probe
The KRT19-PFKP Fusion FISH Probe is used to confirm a fusion of the KRT19 and PFKP genes. The fusion of the KRT19 and PFKP genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KRT19-PFKP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-RERE | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-REOR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-REGO | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-REGR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-REAQ | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-ORRE | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-OROR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-ORGO | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-ORAQ | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GORE | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GOOR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GOGO | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GOGR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GOAQ | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GRRE | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GROR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GRGO | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GRGR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-GRAQ | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-AQRE | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-AQOR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-AQGO | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-AQGR | 20 (40 μL) | 200 μL |
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| KRT19-PFKP-20-AQAQ | 20 (40 μL) | 200 μL |
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KRT19 Gene Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 19
Chromosome: CHR17: 39679868 -39684641
Locus: 17q21.2
PFKP Gene Summary
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Name: Phosphofructokinase, Platelet
Chromosome: CHR10: 3109711 -3178997
Locus: 10p15.2
Gene Diseases
The KRT19 PFKP Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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