KRT19-EIF2AK2 Fusion FISH Probe
The KRT19-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the KRT19 and EIF2AK2 genes. The fusion of the KRT19 and EIF2AK2 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KRT19-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| KRT19-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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KRT19 Gene Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 19
Chromosome: CHR17: 39679868 -39684641
Locus: 17q21.2
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The KRT19 EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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