KRT19-CCT5 Fusion FISH Probe
The KRT19-CCT5 Fusion FISH Probe is used to confirm a fusion of the KRT19 and CCT5 genes. The fusion of the KRT19 and CCT5 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KRT19-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| KRT19-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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KRT19 Gene Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 19
Chromosome: CHR17: 39679868 -39684641
Locus: 17q21.2
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The KRT19 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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