KRT16-CCT5 Fusion FISH Probe
The KRT16-CCT5 Fusion FISH Probe is used to confirm a fusion of the KRT16 and CCT5 genes. The fusion of the KRT16 and CCT5 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KRT16-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| KRT16-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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KRT16 Gene Summary
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 16
Chromosome: CHR17: 39766030 -39769079
Locus: 17q21.2
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The KRT16 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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