KRT14-ARFGEF2 Fusion FISH Probe
The KRT14-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the KRT14 and ARFGEF2 genes. The fusion of the KRT14 and ARFGEF2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KRT14-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| KRT14-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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KRT14 Gene Summary
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 14
Chromosome: CHR17: 39738530 -39743147
Locus: 17q21.2
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The KRT14 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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