KRT10-ARFGEF2 Fusion FISH Probe
The KRT10-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the KRT10 and ARFGEF2 genes. The fusion of the KRT10 and ARFGEF2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KRT10-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KRT10-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
|
KRT10 Gene Summary
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 10
Chromosome: CHR17: 38974368 -38978863
Locus: 17q21.2
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The KRT10 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|