KPNA6-ZCCHC17 Fusion FISH Probe
The KPNA6-ZCCHC17 Fusion FISH Probe is used to confirm a fusion of the KPNA6 and ZCCHC17 genes. The fusion of the KPNA6 and ZCCHC17 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KPNA6-ZCCHC17-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-RERE | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-REOR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-REGO | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-REGR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-REAQ | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-ORRE | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-OROR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-ORGO | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-ORAQ | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GORE | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GOOR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GOGO | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GOGR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GOAQ | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GRRE | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GROR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GRGO | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GRGR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-GRAQ | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-AQRE | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-AQOR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-AQGO | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-AQGR | 20 (40 μL) | 200 μL |
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| KPNA6-ZCCHC17-20-AQAQ | 20 (40 μL) | 200 μL |
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KPNA6 Gene Summary
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
Gene Name: Karyopherin Subunit Alpha 6
Chromosome: CHR1: 32573643 -32642168
Locus: 1p35.2
ZCCHC17 Gene Summary
The Zinc Finger CCHC-type Containing 17 (ZCCHC17) gene is located on chr1 :31769841-31837780 at 1p35.2.
Gene Name: Zinc Finger CCHC-type Containing 17
Chromosome: CHR1: 31769841 -31837780
Locus: 1p35.2
Gene Diseases
The KPNA6 ZCCHC17 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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