KPNA6-TRAIP Fusion FISH Probe
The KPNA6-TRAIP Fusion FISH Probe is used to confirm a fusion of the KPNA6 and TRAIP genes. The fusion of the KPNA6 and TRAIP genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KPNA6-TRAIP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KPNA6-TRAIP-20-AQAQ | 20 (40 μL) | 200 μL |
|
TRAIP Gene Summary
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: TRAF Interacting Protein
Chromosome: CHR3: 49866027 -49893992
Locus: 3p21.31
KPNA6 Gene Summary
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
Gene Name: Karyopherin Subunit Alpha 6
Chromosome: CHR1: 32573643 -32642168
Locus: 1p35.2
Gene Diseases
The KPNA6 TRAIP Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|