KPNA3-MLNR Fusion FISH Probe
The KPNA3-MLNR Fusion FISH Probe is used to confirm a fusion of the KPNA3 and MLNR genes. The fusion of the KPNA3 and MLNR genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KPNA3-MLNR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-RERE | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-REOR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-REGO | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-REGR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-REAQ | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-ORRE | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-OROR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-ORGO | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-ORAQ | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GORE | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GOOR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GOGO | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GOGR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GOAQ | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GRRE | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GROR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GRGO | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GRGR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-GRAQ | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-AQRE | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-AQOR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-AQGO | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-AQGR | 20 (40 μL) | 200 μL |
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| KPNA3-MLNR-20-AQAQ | 20 (40 μL) | 200 μL |
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MLNR Gene Summary
Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a motilin receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]
Gene Name: Motilin Receptor
Chromosome: CHR13: 49794473 -49796513
Locus: 13q14.2
KPNA3 Gene Summary
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. [provided by RefSeq, Jan 2009]
Gene Name: Karyopherin Subunit Alpha 3
Chromosome: CHR13: 50273442 -50367057
Locus: 13q14.2
Gene Diseases
The KPNA3 MLNR Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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