KPNA1-CHRNA9 Fusion FISH Probe
The KPNA1-CHRNA9 Fusion FISH Probe is used to confirm a fusion of the KPNA1 and CHRNA9 genes. The fusion of the KPNA1 and CHRNA9 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KPNA1-CHRNA9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-RERE | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-REOR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-REGO | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-REGR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-REAQ | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-ORRE | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-OROR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-ORGO | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-ORAQ | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GORE | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GOOR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GOGO | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GOGR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GOAQ | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GRRE | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GROR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GRGO | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GRGR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-GRAQ | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-AQRE | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-AQOR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-AQGO | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-AQGR | 20 (40 μL) | 200 μL |
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| KPNA1-CHRNA9-20-AQAQ | 20 (40 μL) | 200 μL |
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KPNA1 Gene Summary
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Name: Karyopherin Subunit Alpha 1
Chromosome: CHR3: 122140747 -122233786
Locus: 3q21.1
CHRNA9 Gene Summary
This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. [provided by RefSeq, Feb 2012]
Gene Name: Cholinergic Receptor Nicotinic Alpha 9 Subunit
Chromosome: CHR4: 40337468 -40356973
Locus: 4p14
Gene Diseases
The KPNA1 CHRNA9 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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