KLK2-CCT5 Fusion FISH Probe
The KLK2-CCT5 Fusion FISH Probe is used to confirm a fusion of the KLK2 and CCT5 genes. The fusion of the KLK2 and CCT5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLK2-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KLK2-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
|
KLK2 Gene Summary
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Gene Name: Kallikrein Related Peptidase 2
Chromosome: CHR19: 51376688 -51383823
Locus: 19q13.33
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The KLK2 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|