KLHL5-LNX1 Fusion FISH Probe
The KLHL5-LNX1 Fusion FISH Probe is used to confirm a fusion of the KLHL5 and LNX1 genes. The fusion of the KLHL5 and LNX1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLHL5-LNX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-RERE | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-REOR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-REGO | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-REGR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-REAQ | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-ORRE | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-OROR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-ORGO | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GORE | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GOOR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GOGO | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GOGR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GRRE | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GROR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GRGO | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GRGR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-AQRE | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-AQOR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-AQGO | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-AQGR | 20 (40 μL) | 200 μL |
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| KLHL5-LNX1-20-AQAQ | 20 (40 μL) | 200 μL |
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KLHL5 Gene Summary
The Kelch Like Family Member 5 (KLHL5) gene is located on chr4 :39046450-39127853 at 4p14.
Gene Name: Kelch Like Family Member 5
Chromosome: CHR4: 39046450 -39127853
Locus: 4p14
LNX1 Gene Summary
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Ligand Of Numb-protein X 1
Chromosome: CHR4: 54326436 -54457724
Locus: 4q12
Gene Diseases
The KLHL5 LNX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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