KLHL3-C16ORF45 Fusion FISH Probe
The KLHL3-C16ORF45 Fusion FISH Probe is used to confirm a fusion of the KLHL3 and C16ORF45 genes. The fusion of the KLHL3 and C16ORF45 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLHL3-C16ORF45-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-RERE | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-REOR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-REGO | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-REGR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-REAQ | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-ORRE | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-OROR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-ORGO | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GORE | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GOOR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GOGO | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GOGR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GRRE | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GROR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GRGO | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GRGR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-AQRE | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-AQOR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-AQGO | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-AQGR | 20 (40 μL) | 200 μL |
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| KLHL3-C16ORF45-20-AQAQ | 20 (40 μL) | 200 μL |
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KLHL3 Gene Summary
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
Gene Name: Kelch Like Family Member 3
Chromosome: CHR5: 136953188 -137071779
Locus: 5q31.2
C16orf45 Gene Summary
The Chromosome 16 Open Reading Frame 45 (C16orf45) gene is located on chr16 :15528324-15682116 at 16p13.11.
Gene Name: Chromosome 16 Open Reading Frame 45
Chromosome: CHR16: 15528324 -15682116
Locus: 16p13.11
Gene Diseases
The KLHL3 C16ORF45 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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