KLHL24-MCF2L2 Fusion FISH Probe
The KLHL24-MCF2L2 Fusion FISH Probe is used to confirm a fusion of the KLHL24 and MCF2L2 genes. The fusion of the KLHL24 and MCF2L2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLHL24-MCF2L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-RERE | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-REOR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-REGO | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-REGR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-REAQ | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-ORRE | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-OROR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-ORGO | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GORE | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GOOR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GOGO | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GOGR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GRRE | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GROR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GRGO | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GRGR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-AQRE | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-AQOR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-AQGO | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-AQGR | 20 (40 μL) | 200 μL |
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| KLHL24-MCF2L2-20-AQAQ | 20 (40 μL) | 200 μL |
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MCF2L2 Gene Summary
The MCF.2 Cell Line Derived Transforming Sequence-like 2 (MCF2L2) gene is located on chr3 :182895830-183145855 at 3q27.1.
Gene Name: MCF.2 Cell Line Derived Transforming Sequence-like 2
Chromosome: CHR3: 182895830 -183145855
Locus: 3q27.1
KLHL24 Gene Summary
The protein encoded by this gene is a ubiquitin ligase substrate receptor and is regulated by autoubiquitination. Variations in the translation initiation codon of this gene have been found, which result in an N-terminally truncated but more stable protein due to loss of the autoubiquitination function. The more stable mutant protein causes an increased ubiquitin and degradation of keratin 14, which leads to skin fragility and the potentially life-threatening disease epidermolysis bullosa. The encoded protein is also involved in the regulation of kainate receptors. [provided by RefSeq, Mar 2017]
Gene Name: Kelch Like Family Member 24
Chromosome: CHR3: 183353410 -183402304
Locus: 3q27.1
Gene Diseases
The KLHL24 MCF2L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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