KLHDC4-MAF Fusion FISH Probe
The KLHDC4-MAF Fusion FISH Probe is used to confirm a fusion of the KLHDC4 and MAF genes. The fusion of the KLHDC4 and MAF genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLHDC4-MAF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-RERE | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-REOR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-REGO | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-REGR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-REAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-ORRE | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-OROR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-ORGO | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GORE | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GOOR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GOGO | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GOGR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GRRE | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GROR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GRGO | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GRGR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-AQRE | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-AQOR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-AQGO | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-AQGR | 20 (40 μL) | 200 μL |
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| KLHDC4-MAF-20-AQAQ | 20 (40 μL) | 200 μL |
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MAF Gene Summary
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Name: MAF BZIP Transcription Factor
Chromosome: CHR16: 79627744 -79634622
Locus: 16q23.2
KLHDC4 Gene Summary
The Kelch Domain Containing 4 (KLHDC4) gene is located on chr16 :87741417-87799598 at 16q24.2.
Gene Name: Kelch Domain Containing 4
Chromosome: CHR16: 87741417 -87799598
Locus: 16q24.2
Gene Diseases
The KLHDC4 MAF Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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