KLHDC4-CA5A Fusion FISH Probe
The KLHDC4-CA5A Fusion FISH Probe is used to confirm a fusion of the KLHDC4 and CA5A genes. The fusion of the KLHDC4 and CA5A genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KLHDC4-CA5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-RERE | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-REOR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-REGO | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-REGR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-REAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-ORRE | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-OROR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-ORGO | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GORE | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GOOR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GOGO | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GOGR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GRRE | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GROR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GRGO | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GRGR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-AQRE | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-AQOR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-AQGO | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-AQGR | 20 (40 μL) | 200 μL |
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| KLHDC4-CA5A-20-AQAQ | 20 (40 μL) | 200 μL |
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CA5A Gene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]
Gene Name: Carbonic Anhydrase 5A
Chromosome: CHR16: 87921624 -87970112
Locus: 16q24.2
KLHDC4 Gene Summary
The Kelch Domain Containing 4 (KLHDC4) gene is located on chr16 :87741417-87799598 at 16q24.2.
Gene Name: Kelch Domain Containing 4
Chromosome: CHR16: 87741417 -87799598
Locus: 16q24.2
Gene Diseases
The KLHDC4 CA5A Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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