KLF12-UCHL3 Fusion FISH Probe
The KLF12-UCHL3 Fusion FISH Probe is used to confirm a fusion of the KLF12 and UCHL3 genes. The fusion of the KLF12 and UCHL3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLF12-UCHL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KLF12-UCHL3-20-AQAQ | 20 (40 μL) | 200 μL |
|
UCHL3 Gene Summary
The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Name: Ubiquitin C-terminal Hydrolase L3
Chromosome: CHR13: 76123926 -76180068
Locus: 13q22.2
KLF12 Gene Summary
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Kruppel Like Factor 12
Chromosome: CHR13: 74260148 -74708066
Locus: 13q22.1
Gene Diseases
The KLF12 UCHL3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|