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KLF12-CAMK2G Fusion FISH Probe

The KLF12-CAMK2G Fusion FISH Probe is used to confirm a fusion of the KLF12 and CAMK2G genes. The fusion of the KLF12 and CAMK2G genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KLF12-CAMK2G-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
KLF12-CAMK2G-20-RERE 20 (40 μL) 200 μL
KLF12-CAMK2G-20-REOR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-REGO 20 (40 μL) 200 μL
KLF12-CAMK2G-20-REGR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-REAQ 20 (40 μL) 200 μL
KLF12-CAMK2G-20-ORRE 20 (40 μL) 200 μL
KLF12-CAMK2G-20-OROR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-ORGO 20 (40 μL) 200 μL
KLF12-CAMK2G-20-ORAQ 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GORE 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GOOR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GOGO 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GOGR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GOAQ 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GRRE 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GROR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GRGO 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GRGR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-GRAQ 20 (40 μL) 200 μL
KLF12-CAMK2G-20-AQRE 20 (40 μL) 200 μL
KLF12-CAMK2G-20-AQOR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-AQGO 20 (40 μL) 200 μL
KLF12-CAMK2G-20-AQGR 20 (40 μL) 200 μL
KLF12-CAMK2G-20-AQAQ 20 (40 μL) 200 μL

CAMK2G Gene Summary

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]

Gene Name: Calcium/calmodulin Dependent Protein Kinase II Gamma

Chromosome: CHR10: 75572258 -75634349

Locus: 10q22.2

KLF12 Gene Summary

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Kruppel Like Factor 12

Chromosome: CHR13: 74260148 -74708066

Locus: 13q22.1

Gene Diseases

The KLF12 CAMK2G Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.