KITLG-TNNC1 Fusion FISH Probe
The KITLG-TNNC1 Fusion FISH Probe is used to confirm a fusion of the KITLG and TNNC1 genes. The fusion of the KITLG and TNNC1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KITLG-TNNC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-RERE | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-REOR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-REGO | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-REGR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-REAQ | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-ORRE | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-OROR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-ORGO | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GORE | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GOOR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GOGO | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GOGR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GRRE | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GROR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GRGO | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GRGR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-AQRE | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-AQOR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-AQGO | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-AQGR | 20 (40 μL) | 200 μL |
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| KITLG-TNNC1-20-AQAQ | 20 (40 μL) | 200 μL |
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KITLG Gene Summary
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: KIT Ligand
Chromosome: CHR12: 88886569 -88974250
Locus: 12q21.32
TNNC1 Gene Summary
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
Gene Name: Troponin C1, Slow Skeletal And Cardiac Type
Chromosome: CHR3: 52485106 -52488057
Locus: 3p21.1
Gene Diseases
The KITLG TNNC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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