KIT-UGT2B7 Fusion FISH Probe
The KIT-UGT2B7 Fusion FISH Probe is used to confirm a fusion of the KIT and UGT2B7 genes. The fusion of the KIT and UGT2B7 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIT-UGT2B7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-RERE | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-REOR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-REGO | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-REGR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-REAQ | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-ORRE | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-OROR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-ORGO | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GORE | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GOOR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GOGO | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GOGR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GRRE | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GROR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GRGO | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GRGR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-AQRE | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-AQOR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-AQGO | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-AQGR | 20 (40 μL) | 200 μL |
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| KIT-UGT2B7-20-AQAQ | 20 (40 μL) | 200 μL |
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KIT Gene Summary
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: KIT Proto-oncogene Receptor Tyrosine Kinase
Chromosome: CHR4: 55524094 -55606881
Locus: 4q12
UGT2B7 Gene Summary
The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]
Gene Name: UDP Glucuronosyltransferase Family 2 Member B7
Chromosome: CHR4: 69962192 -69978705
Locus: 4q13.2
Gene Diseases
The KIT UGT2B7 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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