KIT-SLC4A4 Fusion FISH Probe
The KIT-SLC4A4 Fusion FISH Probe is used to confirm a fusion of the KIT and SLC4A4 genes. The fusion of the KIT and SLC4A4 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIT-SLC4A4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-RERE | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-REOR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-REGO | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-REGR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-REAQ | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-ORRE | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-OROR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-ORGO | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GORE | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GOOR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GOGO | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GOGR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GRRE | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GROR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GRGO | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GRGR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-AQRE | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-AQOR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-AQGO | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-AQGR | 20 (40 μL) | 200 μL |
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| KIT-SLC4A4-20-AQAQ | 20 (40 μL) | 200 μL |
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KIT Gene Summary
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: KIT Proto-oncogene Receptor Tyrosine Kinase
Chromosome: CHR4: 55524094 -55606881
Locus: 4q12
SLC4A4 Gene Summary
This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Name: Solute Carrier Family 4 Member 4
Chromosome: CHR4: 72053002 -72437804
Locus: 4q13.3
Gene Diseases
The KIT SLC4A4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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