KIF5B-MET Fusion FISH Probe
The KIF5B-MET Fusion FISH Probe is used to confirm a fusion of the KIF5B and MET genes. The fusion of the KIF5B and MET genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIF5B-MET-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-RERE | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-REOR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-REGO | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-REGR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-REAQ | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-ORRE | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-OROR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-ORGO | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GORE | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GOOR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GOGO | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GOGR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GRRE | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GROR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GRGO | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GRGR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-AQRE | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-AQOR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-AQGO | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-AQGR | 20 (40 μL) | 200 μL |
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| KIF5B-MET-20-AQAQ | 20 (40 μL) | 200 μL |
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KIF5B Gene Summary
The Kinesin Family Member 5B (KIF5B) gene is located on chr10 :32297937-32345371 at 10p11.22.
Gene Name: Kinesin Family Member 5B
Chromosome: CHR10: 32297937 -32345371
Locus: 10p11.22
MET Gene Summary
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
Gene Name: MET Proto-oncogene, Receptor Tyrosine Kinase
Chromosome: CHR7: 116312458 -116438440
Locus: 7q31.2
Gene Diseases
The KIF5B MET Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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