KIF21A-CPM Fusion FISH Probe
The KIF21A-CPM Fusion FISH Probe is used to confirm a fusion of the KIF21A and CPM genes. The fusion of the KIF21A and CPM genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIF21A-CPM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-RERE | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-REOR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-REGO | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-REGR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-REAQ | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-ORRE | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-OROR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-ORGO | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GORE | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GOOR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GOGO | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GOGR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GRRE | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GROR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GRGO | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GRGR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-AQRE | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-AQOR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-AQGO | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-AQGR | 20 (40 μL) | 200 μL |
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| KIF21A-CPM-20-AQAQ | 20 (40 μL) | 200 μL |
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CPM Gene Summary
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase M
Chromosome: CHR12: 69244955 -69357020
Locus: 12q15
KIF21A Gene Summary
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
Gene Name: Kinesin Family Member 21A
Chromosome: CHR12: 39687029 -39837192
Locus: 12q12
Gene Diseases
The KIF21A CPM Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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