KIDINS220-SOX7 Fusion FISH Probe
The KIDINS220-SOX7 Fusion FISH Probe is used to confirm a fusion of the KIDINS220 and SOX7 genes. The fusion of the KIDINS220 and SOX7 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIDINS220-SOX7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-RERE | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-REOR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-REGO | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-REGR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-REAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-ORRE | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-OROR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-ORGO | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GORE | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GOOR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GOGO | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GOGR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GRRE | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GROR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GRGO | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GRGR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-AQRE | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-AQOR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-AQGO | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-AQGR | 20 (40 μL) | 200 μL |
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| KIDINS220-SOX7-20-AQAQ | 20 (40 μL) | 200 μL |
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KIDINS220 Gene Summary
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Name: Kinase D Interacting Substrate 220
Chromosome: CHR2: 8868986 -8977755
Locus: 2p25.1
SOX7 Gene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. [provided by RefSeq, Jul 2008]
Gene Name: SRY-box 7
Chromosome: CHR8: 10581277 -10588022
Locus: 8p23.1
Gene Diseases
The KIDINS220 SOX7 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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