KIDINS220-EYS Fusion FISH Probe
The KIDINS220-EYS Fusion FISH Probe is used to confirm a fusion of the KIDINS220 and EYS genes. The fusion of the KIDINS220 and EYS genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIDINS220-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| KIDINS220-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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KIDINS220 Gene Summary
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Name: Kinase D Interacting Substrate 220
Chromosome: CHR2: 8868986 -8977755
Locus: 2p25.1
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The KIDINS220 EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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