KIDINS220-COLEC11 Fusion FISH Probe
The KIDINS220-COLEC11 Fusion FISH Probe is used to confirm a fusion of the KIDINS220 and COLEC11 genes. The fusion of the KIDINS220 and COLEC11 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KIDINS220-COLEC11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-RERE | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-REOR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-REGR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-OROR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GROR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| KIDINS220-COLEC11-20-AQAQ | 20 (40 μL) | 200 μL |
|
KIDINS220 Gene Summary
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Name: Kinase D Interacting Substrate 220
Chromosome: CHR2: 8868986 -8977755
Locus: 2p25.1
COLEC11 Gene Summary
This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Collectin Subfamily Member 11
Chromosome: CHR2: 3642636 -3692047
Locus: 2p25.3
Gene Diseases
The KIDINS220 COLEC11 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|