KIAA1949-TNXB Fusion FISH Probe
The KIAA1949-TNXB Fusion FISH Probe is used to confirm a fusion of the KIAA1949 and TNXB genes. The fusion of the KIAA1949 and TNXB genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA1949-TNXB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA1949-TNXB-20-AQAQ | 20 (40 μL) | 200 μL |
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TNXB Gene Summary
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tenascin XB
Chromosome: CHR6_cox_hap2: 3479582 -3547813
Locus: 6p21.33-p21.32
Gene Diseases
The KIAA1949 TNXB Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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