KIAA1598-PRDX3 Fusion FISH Probe
The KIAA1598-PRDX3 Fusion FISH Probe is used to confirm a fusion of the KIAA1598 and PRDX3 genes. The fusion of the KIAA1598 and PRDX3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA1598-PRDX3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA1598-PRDX3-20-AQAQ | 20 (40 μL) | 200 μL |
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PRDX3 Gene Summary
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014]
Gene Name: Peroxiredoxin 3
Chromosome: CHR10: 120927214 -120938345
Locus: 10q26.11
Gene Diseases
The KIAA1598 PRDX3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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