KIAA1217-SPAG6 Fusion FISH Probe
The KIAA1217-SPAG6 Fusion FISH Probe is used to confirm a fusion of the KIAA1217 and SPAG6 genes. The fusion of the KIAA1217 and SPAG6 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KIAA1217-SPAG6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-RERE | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-REOR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-REGO | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-REGR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-REAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-ORRE | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-OROR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-ORGO | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-ORAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GORE | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GOOR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GOGO | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GOGR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GOAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GRRE | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GROR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GRGO | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GRGR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-GRAQ | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-AQRE | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-AQOR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-AQGO | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-AQGR | 20 (40 μL) | 200 μL |
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| KIAA1217-SPAG6-20-AQAQ | 20 (40 μL) | 200 μL |
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SPAG6 Gene Summary
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Sperm Associated Antigen 6
Chromosome: CHR10: 22634398 -22706539
Locus: 10p12.2
KIAA1217 Gene Summary
The (KIAA1217) gene is located on chr10 :23983674-24836772 at 10p12.2-p12.1.
Gene Name:
Chromosome: CHR10: 23983674 -24836772
Locus: 10p12.2-p12.1
Gene Diseases
The KIAA1217 SPAG6 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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